PRP (Platelet Rich Plasma) and PRF (Platelet Rich Fibrin) are both autologous (meaning derived from a patient's own body) treatments used in regenerative and cosmetic medicine and have similar names, but they differ in their composition and preparation methods. PRP is a concentration of platelets and growth factors obtained from a patient's own blood. The blood is drawn and then centrifuged to separate the platelets and growth factors from other components of the blood. The resulting concentrate, which is rich in platelets, is then injected into the patient's body at the site of injury or damage or in tissues that could benefit from rejuvenation. PRP is often used to accelerate healing and reduce inflammation in soft tissue injuries, osteoarthritis, and other musculoskeletal conditions. Cosmetically it is used for hair regrowth, skin rejuvenation and vaginal rejuvenation. PRF, on the other hand, is a fibrin clot that contains a higher concentration of platelets, leukocytes, and growth factors than PRP. PRF is prepared by centrifuging the patient's blood without adding any anticoagulants or other substances. The fibrin clot that forms at the bottom of the tube contains a higher concentration of platelets and growth factors than PRP. PRF is used in various dental and surgical procedures, such as bone grafting and implant placement, to promote healing and tissue regeneration. It has a slower, more prolonged release of growth factors compared to PRP which may lead to improve results. In summary, PRP and PRF are both autologous treatments used in regenerative medicine, but they differ in their composition and preparation methods. PRP is a concentrate of platelets and growth factors obtained by centrifuging the patient's blood, while PRF is a fibrin clot that forms naturally during centrifugation and contains a higher concentration of platelets and growth factors. At Bespoke Skin MD, we have been offering both PRP and PRF for 5 years and have experience in hair regrowth, skin rejuvenation, stretch mark treatment, tear trough treatment, vaginal rejuvenation, Oshot and Pshot.